Cranial neural crest cells are implicated in multiple transcriptional events at the different stages of differentiation during development.The alteration of some transcription factors expressed during neural crest development, like PAX7, could be implicated in Antenna Balun the etiology of face malformation in murine models.Epigenetic regulation ha
Bone non-unions resulting from severe traumatic injuries pose significant clinical challenges, and the biological factors that drive progression towards and healing from these injuries are still not well understood.Recently, a dysregulated systemic immune response following musculoskeletal trauma has been identified as a contributing factor for poo
IntroductionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of coronavirus disease 2019 (COVID-19), has infected millions of individuals worldwide, which poses a severe threat to human health.COVID-19 is a systemic ailment affecting various tissues and organs, including the lungs and liver.Intrahepatic cholangiocarcin
Introduction: Here, the discussion focused on the function and possible mechanism of cancer stem cell-like cells (CSCs)-derived exosomal CDKN2B-AS1 in thyroid cancer.Methods: Specifically, the bioinformatics analysis, dual-luciferase reporter assay and RT-qPCR were conducted to obtain the expression and regulation of CDKN2B-AS1, and the downstream
In this article, we propose a special case of two-echelon location-routing problem (2E-LRP) in cash-in-transit (CIT) sector.To tackle this realistic problem and to make the model applicable, a rich LRP considering several existing real-life variants and characteristics named BO-2E-PCLRPSD-TW including different objective functions, multiple echelon